Copaiba/BCP

Copaifera is a tropical tree commonly found in Brazil, specifically in the central and western region of the Amazon, and western Africa. It has been used in folk medicine for centuries in wound healing and the treatment of numerous disorders, such as urinary, respiratory, skin and inflammatory conditions that several studies have corroborated(1).  Those studies have shown Copaiba to be a powerful anti-inflammatory, anti-oxidant and anti-microbial agent – all very desirable actions for skincare.

The major components of Copaiba include various terpenoids with Beta-Caryophyllene (BCP) the most prominent. BCP is a sesquiterpene but also a cannabinoid and has been shown to effect its anti-inflammatory activities as a cannabinoid CB₂ receptor-selective accounting for a large part of  the whole copaiba oil anti-inflammatory benefits, but not the full effect of copaiba oil. (2)

Furthermore, sesquiterpenes have the ability of deleting faulty information in cellular memory restoring powerful cellular regeneration capacity.

What is more, Copaiba is a magnifier for other skincare actives as it significantly increases penetration into the skin.

Because of this and because Copaiba and CBD attack inflammation and oxidative stress in different ways, our Revive oil offers synergistic anti-oxidant and anti-inflammatory benefits.

Finally, it has also been shown to be extremely safe and biocompatible.

What we love most about copaiba:

• It is widely touted as one of the best non-corticosteroids anti-inflammatory substance reducing aging-causing systemic inflammation but also surface irritation (2)
• It is also a great anti-oxidant that repairs faulty information in cellular memory restoring powerful cellular skin anti-aging regeneration capacity (1).
• Promotes healing of skin injuries including scars (4)
• It is also a disinfectant that assist in cleaning out skin injuries preventing infections but also eliminating impurities that cause dull skin (5)
• Excellent emollient (moisturizer) (1)
• Astringent – shrinks skin tissue and pores for a smooth completion (1)

REFERENCES

1.Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins Lidiam Maia Leandro , et al.

2.The cannabinoid CB₂ receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in models of inflammatory and neuropathic pain. Klauke AL

3.Dias-da-Silva MA, Pereira AC, Marin MC, Salgado MA. The influence of topic and systemic administration of copaiba oil on the alveolar wound healing after tooth extraction. J Clin Exp Dent. 2013;5(4):e169–73.

4.Brazilian medicinal plants with corroborated anti-inflammatory activities: a review. Ribeiro, VP et al

5.Dias DS, Fontes LB, Crotti AE, Aarestrup BJ, Aarestrup FM, da Silva Filho AA. Copaiba oil suppresses inflammatory cytokines in splenocytes of C57Bl/6 models with autoimmune encephalomyelitis (EAE). Molecules. 2014;19(8):12814–26.

6.Paiva LA, Gurgel LA, Campos AR, Silveira ER, Rao VS. Attenuation of ischemia/reperfusion-induced intestinal injury by oleo-resin from Copaifera langsdorffii in models. Life Sci. 2004;75(16):1979–87.

7.de Lima Silva JJ, Guimarães SB, da Silveira ER, de Vasconcelos PR, Lima GG, Torres SM, et al. Effects of Copaifera langsdorffii Desf. On ischemia-reperfusion of randomized skin flaps. Aesthet Plast Surg. 2009;33(1):104–9.

8.Yasojima EY, Teixeira RK, Houat Ade P, Costa FL, Silveira EL, Brito MV, et al. Effect of copaiba oil on correction of abdominal wall defect treated with the use of polypropylene/polyglecaprone mesh. Acta Cir Bras. 2013;28(2):131–5.